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Merck

MAP2K5

mitogen-activated protein kinase kinase 5

Sinônimos:
HsT17454, MAPKK5, MEK5, PRKMK5
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5607) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]
  • Mouse(23938) mitogen-activated protein kinase kinase 5
  • Rat(29568) mitogen activated protein kinase kinase 5
  • Zebrafish(100007679) mitogen-activated protein kinase kinase 5
  • domestic cat(101100725) mitogen-activated protein kinase kinase 5
  • cow(100295732) mitogen-activated protein kinase kinase 5
  • Horse(100052849) mitogen-activated protein kinase kinase 5
  • dog(609559) mitogen-activated protein kinase kinase 5
  • chicken(415557) mitogen-activated protein kinase kinase 5
  • sheep(101104069) mitogen-activated protein kinase kinase 5
  • Domestic Rabbit(100358715) mitogen-activated protein kinase kinase 5
  • naked mole-rat(101711080) mitogen-activated protein kinase kinase 5
  • domestic guinea pig(100732076) mitogen-activated protein kinase kinase 5

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
ANTI-MOUSE MAP2K5 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human, mouse
Aplicação
western blot
Anti-MEK5 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
Monoclonal Anti-MAP2K5 antibody produced in mouse, clone M1-E6, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
PD 98,059, solid,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human MAP2K5,
Espécies
human
MISSION® esiRNA, targeting mouse Map2k5,
Espécies
mouse