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Merck

KCNN2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

Sinônimos:
KCa2.2, SK2, SKCA2, SKCa 2, hSK2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(3781) Summary: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
  • Mouse(140492) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • Rat(54262) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • chicken(395579) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • cow(404177) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • domestic cat(101099926) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • dog(474640) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • sheep(101105660) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • domestic guinea pig(100734732) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • naked mole-rat(101725711) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-SK2 (KCa2.2) Antibody, clone K78/29, clone K78/29, from mouse,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-Potassium Channel SK2 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reatividade de espécies
human, rat
Aplicação
western blot
Anti-KCNN2 antibody produced in rabbit, IgG fraction of antiserum,
Reatividade de espécies
human, yeast
Aplicação
immunohistochemistry
western blot
Anti-KCNN2 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
immunohistochemistry
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Kcnn2,
Espécies
mouse
MISSION® esiRNA, targeting human KCNN2,
Espécies
human