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Merck

GPX1

glutathione peroxidase 1

Sinônimos:
GPXD, GSHPX1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(2876) Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14775) glutathione peroxidase 1
  • Rat(24404) glutathione peroxidase 1
  • Thale Cress(817046) phospholipid hydroperoxide glutathione peroxidase 1
  • chicken(100857115) glutathione peroxidase 1
  • domestic cat(101083751) glutathione peroxidase 1
  • cow(281209) glutathione peroxidase 1
  • Horse(100053396) glutathione peroxidase 1
  • dog(442961) glutathione peroxidase 1
  • sheep(100820742) glutathione peroxidase 1
  • Domestic Rabbit(100009258) glutathione peroxidase 1
  • domestic guinea pig(100729115) glutathione peroxidase 1
  • naked mole-rat(101710466) glutathione peroxidase 1

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-GPX1 Antibody, clone 1J19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
canine, feline, human, monkey, porcine
Aplicação
immunocytochemistry
immunohistochemistry

western blot
ANTI-FLAG® M2-Peroxidase (HRP) monoclonal, clone M2, purified immunoglobulin, buffered aqueous glycerol solution,
Reatividade de espécies
all
Aplicação
ELISA
Anti-GPX1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
alligator, human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-Glutathione peroxidase 1 (ISO1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, pig
Aplicação
ELISA
immunohistochemistry

western blot
Anti-Gpx1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
bovine, mouse, rat
Aplicação
ELISA
western blot

Proteins

Número do produto
Descrição
Espécies
GPX1 human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human GPX1,
Espécies
human