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Merck

GDF5

growth differentiation factor 5

Sinônimos:
BDA1C, BMP14, CDMP1, LAP4, OS5, SYM1B, SYNS2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(8200) Summary: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. [provided by RefSeq, Jul 2008]
  • Mouse(14563) growth differentiation factor 5
  • Rat(252835) growth differentiation factor 5
  • Zebrafish(30195) growth differentiation factor 5
  • chicken(374249) growth differentiation factor 5
  • dog(485850) growth differentiation factor 5
  • Horse(100034228) growth differentiation factor 5
  • cow(539559) growth differentiation factor 5
  • domestic cat(101081533) growth differentiation factor 5
  • naked mole-rat(101696976) growth differentiation factor 5
  • domestic guinea pig(100723808) growth differentiation factor 5
  • sheep(101116499) growth differentiation factor 5
  • Domestic Rabbit(100328897) growth differentiation factor 5

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-GDF5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-GDF5OS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry

Proteins

Número do produto
Descrição
Espécies
BMP-14 (GDF-5/CDMP-1) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Espécies
human
GDF-5 mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Espécies
mouse

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Gdf5,
Espécies
mouse
MISSION® esiRNA, targeting human GDF5,
Espécies
human