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Merck

GABRA5

gamma-aminobutyric acid (GABA) A receptor, alpha 5

Sinônimos:
Espécies:
ID UniProtKB:
ID do gene:
  • Human(2558) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
  • Mouse(110886) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
  • Rat(29707) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Zebrafish(799124) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • dog(488688) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • cow(523515) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Horse(100050880) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic cat(101090773) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • chicken(418684) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • sheep(101115159) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Domestic Rabbit(100340943) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • naked mole-rat(101712275) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic guinea pig(100729411) gamma-aminobutyric acid (GABA) A receptor, alpha 5

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Espécies
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Espécies
human
Isoguvacine hydrochloride, solid,
Espécies
human
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human
γ-Aminobutyric acid, ≥99%,
Espécies
human, rat

Small Molecule - Allosteric Modulator

Número do produto
Descrição
Espécies
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Espécies
human
Midazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human
Diazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human
Oxazepam solution, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human
Alprazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Ro 15-4513, solid,
Espécies
rat, human
Picrotoxin, powder,
Espécies
human
SR-95531, ≥98% (HPLC), powder,
Espécies
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Espécies
human
Ganaxolone, ≥98% (HPLC), solid,
Espécies
human, mouse

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-GABA A Receptor α 5 Antibody, Chemicon®, from rabbit,
Reatividade de espécies
mouse, rat
Aplicação
western blot
Anti-GABRA5 (ab2) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
guinea pig, human, mouse, rabbit, rat
Aplicação
immunohistochemistry
western blot
Monoclonal Anti-GABA A Receptor antibody produced in mouse, clone S415-24,
Reatividade de espécies
human, mouse
Aplicação
immunofluorescence
western blot
Anti-GABRA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Monoclonal Anti-GABA A Receptor-Atto 594 antibody produced in mouse, clone S415-24,
Reatividade de espécies
human, mouse
Aplicação
immunofluorescence
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
NO-711 hydrochloride, ≥98% (HPLC),
Espécies
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human

Small Molecule - Ligand

Número do produto
Descrição
Espécies
L-655,708, ≥98% (HPLC), powder,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human GABRA5,
Espécies
human