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Merck

DDR2

discoidin domain receptor tyrosine kinase 2

Sinônimos:
MIG20a, NTRKR3, TKT, TYRO10
Espécies:
Human DDR2 (4921), Mouse Ddr2 (18214), Rat Ddr2 (685781), Zebrafish ddr2 (559428), dog DDR2 (478987), chicken DDR2 (396404), Horse DDR2 (100058300), cow DDR2 (533523), domestic cat DDR2 (101085267), sheep DDR2 (101109754) ...Mais
ID UniProtKB:
Q16832, Q7Z730
ID do gene:
  • Human(4921) Summary: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(18214) discoidin domain receptor family, member 2
  • Rat(685781) discoidin domain receptor tyrosine kinase 2
  • Zebrafish(559428) discoidin domain receptor family, member 2
  • dog(478987) discoidin domain receptor tyrosine kinase 2
  • chicken(396404) discoidin domain receptor tyrosine kinase 2
  • Horse(100058300) discoidin domain receptor tyrosine kinase 2
  • cow(533523) discoidin domain receptor tyrosine kinase 2
  • domestic cat(101085267) discoidin domain receptor tyrosine kinase 2
  • sheep(101109754) discoidin domain receptor tyrosine kinase 2
  • naked mole-rat(101712349) discoidin domain receptor tyrosine kinase 2
  • domestic guinea pig(100729537) discoidin domain receptor tyrosine kinase 2

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ELISA

Número do produto
Descrição
Espécies
RAB1007
Phosphotyrosine DDR2 / Discoidin domain-containing Receptor 2 ELISA Kit, ,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
HPA070112
Anti-DDR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
SAB5702493
Anti-DDR2 Antibody, clone 1M8U7, Rabbit Monoclonal, ,
Reatividade de espécies
human, rat
Aplicação
western blot
SAB5300116
Monoclonal Anti-DDR2 antibody produced in mouse, clone 3B11E4, ascites fluid,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB1305077
MONOCLONAL ANTI-DDR2 antibody produced in mouse, clone 484CT5.5.4, crude ascites, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot

esiRNA

Número do produto
Descrição
Espécies
EMNC007421
MISSION® esiRNA, targeting mouse Ddr2,
Espécies
mouse
EHU047831
MISSION® esiRNA, targeting human DDR2,
Espécies
human
EMU057881
MISSION® esiRNA, targeting mouse Ddr2,
Espécies
mouse