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Merck

CHRNA3

cholinergic receptor, nicotinic, alpha 3 (neuronal)

Sinônimos:
LNCR2, NACHRA3, PAOD2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
  • Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
  • Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
  • dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • chicken(386578) cholinergic receptor, nicotinic, alpha 3
  • naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
(±)-Nicotine, ≥99% (TLC), liquid,
Espécies
human, rat
Cloreto de carbamoilcolina, ≥98% (titration), crystalline,
Espécies
human, mouse, rat
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Espécies
rat, human
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Espécies
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Espécies
human, mouse, rat

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Cytisine, ≥99%, powder,
Espécies
rat
(±)-Nicotine, ≥99% (TLC), liquid,
Espécies
human, rat
Cloreto de carbamoilcolina, ≥98% (titration), crystalline,
Espécies
human, mouse, rat
Mecamylamine hydrochloride, ,
Espécies
human
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Espécies
rat, human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CHRNA3 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
dog, human, rabbit
Aplicação
western blot
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
chicken, eel, human
Aplicação
immunohistochemistry

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Tetraethylammonium chloride, ≥98% (titration),
Espécies
human
Hexamethonium bromide, ,
Espécies
human
Hexamethonium chloride, solid (hygroscopic),
Espécies
human
Kynurenic acid, ≥98%,
Espécies
rat, human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CHRNA3,
Espécies
human
MISSION® esiRNA, targeting mouse Chrna3,
Espécies
mouse