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Merck

CDC25A

cell division cycle 25A

Sinônimos:
CDC25A2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(993) Summary: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12530) cell division cycle 25A
  • Rat(171102) cell division cycle 25A
  • chicken(420375) cell division cycle 25 homolog A (S. pombe)
  • cow(520188) cell division cycle 25 homolog A (S. pombe)
  • Horse(100064223) cell division cycle 25 homolog A (S. pombe)
  • domestic cat(101098445) cell division cycle 25 homolog A (S. pombe)
  • dog(484780) cell division cycle 25 homolog A (S. pombe)
  • sheep(101113178) cell division cycle 25 homolog A (S. pombe)
  • domestic guinea pig(100721008) cell division cycle 25A
  • naked mole-rat(101699133) cell division cycle 25A

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Monoclonal Anti-CDC25A antibody produced in mouse, clone 3D5, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
proximity ligation assay

western blot
Anti-phospho-CDC25A (pSer124) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot
Anti-CDC25A antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot
Anti-Phospho-CDC25A-S76 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
Anti-CDC25A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
NSC 95397, ≥97% (HPLC),
Espécies
human

Proteins

Número do produto
Descrição
Espécies
CDC25A, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CDC25A,
Espécies
human
MISSION® esiRNA, targeting mouse Cdc25a,
Espécies
mouse