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Merck

CBX3

chromobox homolog 3

Sinônimos:
HECH, HP1-GAMMA, HP1Hs-gamma
Espécies:
ID UniProtKB:
ID do gene:
  • Human(11335) Summary: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
  • Mouse(12417) chromobox 3
  • Rat(297093) chromobox homolog 3
  • naked mole-rat(101714000) chromobox homolog 3
  • domestic guinea pig(100714020) chromobox homolog 3
  • sheep(101106931) chromobox homolog 3
  • chicken(395355) chromobox homolog 3
  • dog(482015) chromobox homolog 3
  • cow(539788) chromobox homolog 3
  • domestic cat(101099363) chromobox homolog 3

Custom & Knockdown Gene Products

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-HP1γ Antibody, clone 42s2, clone 42s2, Upstate®, from mouse,
Reatividade de espécies
human, mouse
Aplicação
ChIP
immunohistochemistry

western blot
Anti-CBX3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Rabbit anti-CBX3 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reatividade de espécies
human
Aplicação
immunohistochemistry
immunoprecipitation (IP)
Anti-HP1γ Antibody, clone 14D3.1, clone 14D3.1, from mouse,
Reatividade de espécies
human, mouse, nonhuman primates, rat
Aplicação
immunocytochemistry
western blot
Anti-HP1 gamma/CBX3 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CBX3,
Espécies
human
MISSION® esiRNA, targeting mouse Ensmusg00000059647,
Espécies
mouse
MISSION® esiRNA, targeting mouse Cbx3,
Espécies
mouse
MISSION® esiRNA, targeting mouse CBX3-PS2, CBX3-PS5,
Espécies
mouse