APC
adenomatous polyposis coli
Sinônimos:
BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
Espécies:
Human APC (324), Mouse Apc (11789), Rat Apc (24205), sheep APC (101104664), domestic guinea pig Apc (100723694), naked mole-rat Apc (101704055), Zebrafish apc (386762), fruit fly Apc (44642), cow APC (533233), Horse APC (100064431) ...Mais
ID UniProtKB:
ID do gene:
- Human(324) Summary: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
- Mouse(11789) adenomatosis polyposis coli
- Rat(24205) adenomatous polyposis coli
- sheep(101104664) adenomatous polyposis coli
- domestic guinea pig(100723694) adenomatous polyposis coli
- naked mole-rat(101704055) adenomatous polyposis coli
- Zebrafish(386762) adenomatosis polyposis coli
- fruit fly(44642) APC-like
- cow(533233) adenomatous polyposis coli
- Horse(100064431) adenomatous polyposis coli
- domestic cat(101096138) adenomatous polyposis coli
- dog(479139) adenomatous polyposis coli
- chicken(415607) adenomatous polyposis coli
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-APC Antibody, clone CC-1, clone CC-1, from mouse,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-APC antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APC (Ab-1) Mouse mAb (FE9), liquid, clone FE9, Calbiochem®,
Reatividade de espécies
human, mouse, rat
Aplicação
Anti-APC Antibody, clone FE9, clone FE9, from mouse,
Reatividade de espécies
human
Aplicação
western blot
Anti-APC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
Cell Lines
Número do produto
Descrição
Espécies