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P6488

Sigma-Aldrich

Monoclonal Anti-Prion Protein antibody produced in mouse

clone F89/160.1.5, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-AA960666, Anti-CD230, Anti-PRIP, Anti-PrP, Anti-PrP<C>, Anti-PrPSc, Anti-Prn-i, Anti-RP23-401J24.1, Anti-Sinc

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About This Item

MDL number:
MFCD01865558
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

F89/160.1.5, monoclonal

form

buffered aqueous solution

mol wt

antigen 27-30 kDa (PrPSc)
antigen 33-35 kDa (PrPC)

species reactivity

sheep, deer, human, bovine

technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

isotype

IgG1

UniProt accession no.

P04156

shipped in

wet ice

storage temp.

−20°C

Gene Information

bovine ... PRNP(281427)
human ... PRNP(5621)
sheep ... PRNP(493887)

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Immunogen

synthetic peptide corresponding to amino acid residues 146-159 of bovine PrP, conjugated to KLH.

Physical form

Solution in phosphate buffered saline, containing 1 mg/mL bovine serum albumin and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shizuyo Sutou et al.
BMC biotechnology, 7, 44-44 (2007-07-28)
Since prion gene-knockout mice do not contract prion diseases and animals in which production of prion protein (PrP) is reduced by half are resistant to the disease, we hypothesized that bovine animals with reduced PrP would be tolerant to BSE.
K I O'Rourke et al.
Journal of clinical microbiology, 36(6), 1750-1755 (1998-06-10)
The transmissible spongiform encephalopathies are a heterogeneous group of fatal neurodegenerative disorders occurring in humans, mink, cats, and ruminant herbivores. The occurrence of novel transmissible spongiform encephalopathies in cattle in the United Kingdom and Europe and in mule deer and

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