- Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates.
Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates.
Chemical communications (Cambridge, England) (2011-10-19)
Andre Jakoblinnert, Radoslav Mladenov, Albert Paul, Fabrizio Sibilla, Ulrich Schwaneberg, Marion B Ansorge-Schumacher, Pablo Domínguez de María
PMID22005469
RÉSUMÉ
The asymmetric reduction of ketones is performed by using lyophilized whole cells in neat substrates with defined water activity (a(w)). Ketones and alcohols prone to be unstable in aqueous media can now be converted via biocatalysis.