- Cytotoxic and Antimigratory Activities of Phenolic Compounds from Dendrobium brymerianum.
Cytotoxic and Antimigratory Activities of Phenolic Compounds from Dendrobium brymerianum.
Evidence-based complementary and alternative medicine : eCAM (2015-02-17)
Pornprom Klongkumnuankarn, Kesarin Busaranon, Pithi Chanvorachote, Boonchoo Sritularak, Vichien Jongbunprasert, Kittisak Likhitwitayawuid
PMID25685168
RÉSUMÉ
Chromatographic separation of a methanol extract prepared from the whole plant of Dendrobium brymerianum led to the isolation of eight phenolic compounds. Among the isolated compounds (1-8), moscatilin (1), gigantol (3), lusianthridin (4), and dendroflorin (6) showed appreciable cytotoxicity against human lung cancer cell lines with IC50 values of 196.7, 23.4, 65.0, and 125.8 μg/mL, respectively, and exhibited antimigratory property at nontoxic concentrations. This study is the first report on the biological activities of this plant.
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