1179333

Dexmedetomidine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : (+)-Medetomidine hydrochloride, (S)-Medetomidine hydrochloride, 4-[(S)-α,2,3-Trimethylbenzyl]imidazole monohydrochloride, 5-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
• Formule empirique (notation de Hill): C₁₃H₁₆N₂ · HCl
• Numéro CAS: 145108-58-3
• Poids moléculaire : 236.74
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: dexmedetomidine, medetomidine
• Fabricant/nom de marque: USP
• Application(s): pharmaceutical (small molecule)
• Format: neat
• InChI: 1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1
• Clé InChI: VPNGEIHDPSLNMU-MERQFXBCSA-N

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexmedetomidine hydrochloride USP reference standard for specified quality tests and assays.

Also used to prepare standard, system suitability, and sensitivity solution for assay and impurity analysis using liquid chromatography method and UV detector according to the given below monographs of United States Pharmacopeia (USP):

• Dexmedetomidine Injection
• Dexmedetomidine Hydrochloride

Actions biochimiques/physiologiques

Dexmedetomidine hydrochloride is a highly potent and selective α2-adrenergic agonist with analgesic and sedative properties, the (+)-isomer of medetomidine. Dexmedetomidine hydrochloride is used clinically as an anesthetic agent to reduce anxiety and tension and promote relaxation and sedation without causing respiratory depression.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H302 - H336 - H411
• Conseils de prudence: P261 - P264 - P271 - P273 - P301 + P312 - P304 + P340 + P312
• Classification des risques: Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT SE 3
• Organes cibles: Central nervous system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable