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Astec® CHIROBIOTIC® TAG Chiral (5 μm) HPLC Columns

L × I.D. 25 cm × 10 mm, HPLC Column

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About This Item

Code UNSPSC :
41115700
eCl@ss :
32110501
Nomenclature NACRES :
SB.52

product name

Astec® Chirobiotic® TAG Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 10 mm

Matériaux

stainless steel column

Agence

suitable for USP L63

Description

HPLC column

Gamme de produits

Astec®

Conditionnement

pkg of 1 ea

Fabricant/nom de marque

Astec®

Paramètres

0-45 °C temperature
241 bar pressure (3500 psi)

Technique(s)

HPLC: suitable
LC/MS: suitable

L × D.I.

25 cm × 10 mm

Matrice

High-purity silica gel particle platform
fully porous particle

Groupe de la matrice active

teicoplanin aglycone phase

Taille des particules

5 μm

Dimension de pores

100 Å

operating pH range

3.0-6.8

Technique de séparation

chiral

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Description générale

The removal of three carbohydrate moieties gives CHIROBIOTIC® TAG complementary selectivity to CHIROBIOTIC® T. Resolution is enhanced toward many of the amino acids, α, β, γ and cyclic, and especially sulfur-containing methionine, histidine and cysteine. A number of neutral molecules like the oxazolidinones, hydantoins and diazepines have shown enhanced resolution and, more remarkably, in the single solvents like methanol, ethanol and acetonitrile. Some acidic molecules have also shown increased selectivity.

  • Bonded phase: Teicoplanin aglycone
  • Operating pH range: 3.0 - 6.8
  • Particle diameter: 5, 10 or 16 μm
  • Pore size: 100 Å

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Informations légales

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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Certificats d'analyse (COA)

Lot/Batch Number
271081-01
264330-01
176983-01
173670-01
169309-01

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Ilaria D'Acquarica et al.
Journal of chromatography. A, 1061(2), 167-173 (2005-01-12)
We describe a new tandem-columns chiral-achiral HPLC arrangement by using a chiral column (CHIROBIOTIC TAG) connected in series with an achiral column (Spherisorb S5 SCX), based on a strong cationic exchange mechanism; this approach is very useful for the analysis
Abdulrahman A Al-Majed
Journal of pharmaceutical and biomedical analysis, 50(1), 96-99 (2009-05-19)
A direct chiral high-performance liquid chromatography (HPLC) method was developed and validated for the resolution and quantification of antiepileptic drug enantiomers, R-(-)- and S-(+)-vigabatrin (gamma-vinyl-gamma-aminobutyric acid) in pharmaceutical products. The separation was optimized on a macrocyclic glycopeptide antibiotic chiral stationary
Markus Fuereder et al.
Journal of chromatography. A, 1236, 123-131 (2012-04-03)
Teicoplanin aglycone-based chromatography columns (Chirobiotic TAG) enable amino acid enantioseparation with aqueous mobile phases, which perfectly accommodates the distinct hydrophilicity of most amino acids. Therefore, this stationary phase constitutes a promising option in particular for preparative-scale separations that require high
Adsorption behavior of a teicoplanin aglycone bonded stationary phase under harsh overload conditions
Bechtold, Matthias, et al.
Journal of Chromatography A, 1154 (1-2), 2477-2286 (2007)
Matthias Bechtold et al.
Journal of chromatography. A, 1113(1-2), 167-176 (2006-02-28)
The suitability of a teicoplanin-aglycone based chiral stationary phase for the simulated moving bed (SMB) enantioseparation of amino acids under enzyme-compatible conditions was shown following a procedure that is based solely on model-based simulations and HPLC experiments. A set of
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