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Merck
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Key Documents

Autres documents

T1782

Sigma-Aldrich

(+)-γ-Tocopherol

≥96% (HPLC)

Synonyme(s) :

gamma-Tocopherol, (R,R,R)-γ-Tocopherol, 7,8-Dimethyltocol

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About This Item

Formule empirique (notation de Hill):
C28H48O2
Numéro CAS:
54-28-4
Poids moléculaire :
416.68
Numéro Beilstein :
93072
Numéro CE :
200-201-5
Numéro MDL:
MFCD00066529
Code UNSPSC :
12352211
eCl@ss :
34058016
ID de substance PubChem :
24899992
Nomenclature NACRES :
NA.79

Pureté

≥96% (HPLC)

Forme

liquid

Technique(s)

HPLC: suitable

Couleur

dark brown
 colorless to dark yellow

Température de stockage

2-8°C

Chaîne SMILES 

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1

InChI

1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/m1/s1

Clé InChI

QUEDXNHFTDJVIY-DQCZWYHMSA-N

Informations sur le gène

human ... HMGCR(3156)

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Catégories apparentées

Application

(+)-γ-Tocopherol has been used:
  • as reference material for the quantification of γ-tocopherol in the oil sample using high performance liquid chromatography with diode array detector (HPLC/DAD)(192}
  • as a component of diet to feed vitamin-E-depleted rats to study its effects
  • as an additive in the feed to study its effects in reducing dietary induced oxidative stress in vivo and improving meat lipid stability in broilers

Actions biochimiques/physiologiques

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble antioxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Various isofroms and analogues of tocopherol have opposing and differentiated regulatory activities in vivo.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Graded dietary levels of RRR-gamma-tocopherol induce a marked increase in the concentrations of alpha-and gamma-tocopherol in nervous tissues, heart, liver and muscle of vitamin-E-deficient rats
Clement M, et al.
Biochimica et biophysica acta. General subjects, 1334(2-3), 173-118 (1997)
Characterization of oil extracted from the kernel of the fruit of cumare?s palm (Astrocaryum chambira Barret)
Ramirez-Nino MA, et al.
Revista da Faculdade de Odontologia de Aracatuba, 71(1), 8415-8422 (2018)
Chandra K Singh et al.
Oncotarget, 5(11), 3651-3661 (2014-07-09)
Studies have shown that vitamin E and selenium possess antiproliferative effects against prostate cancer (PCa). However, results from the Selenium and Vitamin E Cancer Prevention Trial (SELECT) suggest that vitamin E (α-tocopheryl acetate; 400 mg) and/or selenium (L-selenomethionine; 200 μg)
The potency of alpha-and gamma-tocopherol, and their combination, in reducing dietary induced oxidative stress in vivo and improving meat lipid stability in broilers
Tomavzin U, et al.
Archiv fur Geflugelkunde, 77, 266-274 (2013)
P C Allen et al.
Poultry science, 81(1), 41-48 (2002-03-12)
In two trials, broiler chickens, processed similarly to those placed in commercial operation, were fed, from 1 d of age, a range (13 to 200 ppm) of DL-alpha-tocopheryl acetate (VE-AC) levels, and the effects on the pathology of Eimeria maxima
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Protocoles

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si

Separation of (±)-α-Tocopherol, analytical standard; Menadione (K3), analytical standard; (+)-γ-Tocopherol, analytical standard; Cholecalciferol (D3), analytical standard

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