SRP6354

CD3E human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Synonyme(s) : T-cell surface glycoprotein CD3 epsilon chain, T3E, TCRE
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: human
• Produit recombinant: expressed in E. coli
• Pureté: ≥90% (SDS-PAGE)
• Forme: liquid
• Poids mol.: 14.1 kDa (127 aa, 23-126 aa + His Tag)
• Conditionnement: pkg of 50 μg
• Concentration: 1 mg/mL
• Numéro d'accès UniProt: P07766
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Informations sur le gène: human ... CD3E(916)

Description

Description générale

CD3E is the CD3-epsilonpolypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor α/β and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. Recombinant human CD3E protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Forme physique

1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, and 10% glycerol.

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable