SML1583

Roseoflavin

≥95% (HPLC)

• Synonyme(s) : 8-Demethyl-8-(dimethylamino)-riboflavin, 8-Dimethylaminoriboflavin
• Formule empirique (notation de Hill): C₁₈H₂₃N₅O₆
• Numéro CAS: 51093-55-1
• Poids moléculaire : 405.41
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥95% (HPLC)
• Forme: powder
• Conditions de stockage: protect from light
• Couleur: faint red to very dark brown-red
• Solubilité: DMSO: 5 mg/mL, clear (warmed)
• Température de stockage: −20°C
• InChI: 1S/C18H23N5O6/c1-8-4-9-11(5-10(8)22(2)3)23(6-12(25)15(27)13(26)7-24)16-14(19-9)17(28)21-18(29)20-16/h4-5,12-13,15,24-27H,6-7H2,1-3H3,(H,21,28,29)
• Clé InChI: IGQLDUYTWDABFK-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

Roseoflavin is an analog of flavin mononucleotide (FMN) and riboflavin with antimicrobial activity. Roseoflavin is converted to the flavin mononucleotide (FMN) analog roseoflavin mononucleotide (RoFMN) by flavokinase and to the flavin adenine dinucleotide (FAD) analog roseoflavin adenine dinucleotide (RoFAD) by FAD synthetase, and acts as a riboflavin antagonist. Roseoflavin is an inhibitor of bacterial riboflavin riboswitches, cis regulatory elements present in non-coding RNA that specifically bind to natural ligands to regulate gene expression. Roseoflavin, converted to RoFMN, blocks the flavin mononucleotide riboswitch-mediated expression of the ribB gene, which is required for riboflavin biosynthesis.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable