SMB01061

Emetine

≥90% (LC/MS-ELSD)

• Synonyme(s) : (-)-Emetine
• Formule empirique (notation de Hill): C₂₉H₄₀N₂O₄
• Numéro CAS: 483-18-1
• Poids moléculaire : 480.64
• Numéro MDL: MFCD00242944
• Code UNSPSC : 12352205
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: plant
• Essai: ≥90% (LC/MS-ELSD)
• Forme: solid
• Poids mol.: 480.64
• Solubilité: water: soluble
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Température de stockage: −20°C
• InChI: 1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1
• Clé InChI: AUVVAXYIELKVAI-CKBKHPSWSA-N

Description

Description générale

Emetine, a pyridoisoquinoline alkaloid, is a bioactive natural compound commonly derived from plants such as Helichrysum revolutum, Sphaerophysa salsula, Coryphantha elephantidens, Uragoga ipecacuanha, Uragoga acuminata and Clonostachys rosea. Current research suggests that this metabolite acts as an inhibitor and may exhibit diverse biological activities, including antiprotozoal, antitumor, anti-inflammatory, anti-infective, antimalarial, and antiviral properties.

Application

Emetine is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and drug discovery research.

Actions biochimiques/physiologiques

Emetine is the principal pyridoisoquinoline of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae.

Emetine is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in eukaryotic cells but not prokaryotic cells.

Caractéristiques et avantages

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Autres remarques

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable