SAB4702047

Monoclonal Anti-CD81 APC-Cyanine7 produced in mouse

• Synonyme(s) : CVID6, S5.7, TAPA1, TSPAN28
• Code UNSPSC : 12352203

Propriétés

• Conjugué: APC-Cy7 conjugate
• Niveau de qualité: 100
• Type de produit anticorps: primary antibodies
• Clone: M38, monoclonal
• Forme: buffered aqueous solution
• Espèces réactives: ( Human), rabbit, ( Cat)
• Technique(s): flow cytometry: suitable
• Isotype: IgG1
• Numéro d'accès UniProt: P60033
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... CD81(975)

Description

Description générale

CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.

Spécificité

The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Immunogène

MOLT-4 (human T-ALL cell line)

Forme physique

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Notes préparatoires

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Stockage et stabilité

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Autres remarques

The antibody solution should be gently mixed before use.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable