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Key Documents

SAB4503227

Sigma-Aldrich

Anti-OR51E2 antibody produced in rabbit

affinity isolated antibody

Synonyme(s) :

HPRAJ, OR51E2, Olfactory receptor 51E2, Olfactory receptor OR11-16, Prostate-specific G-protein coupled receptor

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

antigen 35 kDa

Espèces réactives

rat, human

Concentration

~1 mg/mL

Technique(s)

ELISA: 1:10000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

Numéro d'accès NCBI

Q9H255

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... O51E2(81285)

Catégories apparentées

Description générale

Anti-OR51E2 Antibody detects endogenous levels of total OR51E2 protein.

OR51E2 (olfactory receptor family 51 subfamily E member 2),also known as PSGR, codes for a G-protein–coupled receptor. It is a member of the odorant receptors family. OR51E2 is present in early endosomes. It is mapped to human chromosome 11p15.

Immunogène

The antiserum was produced against synthesized peptide derived from human OR51E2.

Immunogen Range: 221-270

Actions biochimiques/physiologiques

OR51E2 (olfactory receptor family 51 subfamily E member 2) helps to mediate rapid, non-genomic, steroidal signaling in prostate cancer cells. It also promotes the growth of early prostate cancer.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes
Gelis L, et al.
The Journal of Biological Chemistry, 291(34), 17772-17786 (2016)
Lian Gelis et al.
Experimental dermatology, 26(7), 569-576 (2017-02-14)
We identified the olfactory receptor 51E2 in human melanoma and have measured both OR51E2 mRNA and protein expression in melanoma tissue sections. qPCR analysis revealed that the receptor is upregulated in melanoma cells compared to normal melanocytes, indicating that OR51E2
The Cancer Genome Atlas Clinical Explorer: a web and mobile interface for identifying clinical-genomic driver associations
Lee H, et al.
Genome Medicine, 7(1), 112-112 (2015)
Nikolina Jovancevic et al.
Frontiers in physiology, 8, 888-888 (2017-12-19)
The odorant receptor 51E2 (OR51E2), which is well-characterized in prostate cancer cells and epidermal pigment cells, was identified for the first time as the most highly expressed OR in human fetal and adult retinal pigment epithelial (RPE) cells. Immunofluorescence staining
Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers
Weng J, et al.
International Journal of Cancer. Journal International Du Cancer, 113(5), 811-818 (2005)
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