SAB4502354

Anti-PKC α antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : KPCA, PKC III, PKC-α, PKC-A, kinase PKC-α
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 76 kDa
• Espèces réactives: human, mouse, rat
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P17252
• Numéro d'accès UniProt: P17252
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... PRKCA(5578)

Description

Description générale

Anti-PKC α Antibody detects endogenous levels of total PKC α protein.

PKC α (protein kinase C α) gene is mapped to 17q24.2. PKC α is expressed in heart, liver, brain and epithelium.

Immunogène

The antiserum was produced against synthesized peptide derived from human PKC alpha.

Immunogen Range: 606-655

Actions biochimiques/physiologiques

PKC (protein kinase C) is known to mediate different cellular processes, such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. While PKC is also associated with the learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC α (protein kinase C α) being one of the isozymes of the PKC family, it catalyzes the phosphorylation of substrates with many peptides.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable