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Key Documents

SAB3700768

Sigma-Aldrich

Anti-Monkey IgG (γ-chain specific)-Biotin antibody produced in goat

affinity isolated antibody, lyophilized powder

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

goat

Conjugué

biotin conjugate

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Forme

lyophilized powder

Espèces réactives

monkey

Technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

Description générale

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chain and two light chains connected by disulfide bond. It is a glycoprotein. IgG is a major class of immunoglobulin.

Spécificité

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Monkey IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Biotin, Anti-Goat Serum, Monkey IgG and Monkey Serum. No reaction was observed against Monkey IgA or Monkey IgM.

Immunogène

Monkey IgG gamma heavy chain

Actions biochimiques/physiologiques

Immunoglobulin G (IgG) mainly helps in immune defense. It participates in hypersensitivity type II and type III. Macaques (rhesus monkeys) and cynomolgus monkeys (cynos) serves as hosts in synthesizing vaccine, transplantation research, studies of viral diseases, pharmacodynamics and pharmacokinetic and safety assessments of therapeutic candidate Abs (antibodies).

Propriétés physiques

Antibody format: IgG

Forme physique

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

Reconstitution

Reconstitute with 1.0 mL deionized water (or equivalent).

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pictogrammes

Skull and crossbonesEnvironment
GHS06,GHS09

Mention d'avertissement

Danger

Mentions de danger

H302,H311,H411

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2

Risques supp

EUH032

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Molecular and functional characterization of cynomolgus monkey IgG subclasses.
Jacobsen FW, et al.
Journal of Immunology, 1001685-1001685 (2010)
Molecular Genetics of Immunoglobulin, 244-244 (1987)
The Immunoglobulins: Structure and Function, 269-269 (1998)
Guidenn Sulbaran et al.
Cell reports. Medicine, 3(2), 100528-100528 (2022-03-03)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused an ongoing global health crisis. Here, we present as a vaccine candidate synthetic SARS-CoV-2 spike (S) glycoprotein-coated lipid vesicles that resemble virus-like particles. Soluble S glycoprotein trimer stabilization by
Specific IgG for cat allergens in patients with allergic conjunctivitis.
Miyama A, et al.
International Ophthalmology, 35(4), 575-586 (2015)
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