SAB3501207

Anti-West Nile Virus Matrix antibody produced in rabbit

affinity isolated antibody

• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: liquid
• Espèces réactives: West Nile virus
• Concentration: 1 mg/mL
• Technique(s): ELISA: suitable
• Isotype: IgG
• Numéro d'accès NCBI: NP_776012
• Numéro d'accès UniProt: P06935
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified

Description

Description générale

West Nile Virus Matrix Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. However, when the viruses are inside of infected cells, the matrix protein exists in its "pre-M" form as a heterodimer with the envelope proteins. Cleavage of the "pre-M" protein to its mature form occurs during release of the virus; this cleavage leas to the dissociation of the heterodimers. The WNV receptor has recently been identified as alpha v beta 3 integrin.

Immunogène

West Nile virus matrix antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of the West Nile virus matrix protein.The immunogen is located within amino acids 220 - 270 of West Nile Virus Matrix.

Application

West Nile virus matrix antibody can be used for the detection of the West Nile virus matrix protein in ELISA. It will detect 10 ng of free peptide at 1 μg/mL.  

Forme physique

Supplied in PBS containing 0.02% sodium azide.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable