Accéder au contenu
Merck
Toutes les photos(4)

Key Documents

View All Documentation

S3626

Sigma-Aldrich

Squalene

≥98%, liquid

Synonyme(s) :

2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(4)

About This Item

Formule linéaire :
[(CH3)2C[=CHCH2CH2C(CH3)]2=CHCH2-]2
Numéro CAS:
111-02-4
Poids moléculaire :
410.72
Numéro Beilstein :
1728919
Numéro CE :
203-826-1
Numéro MDL:
MFCD00008912
Code UNSPSC :
12352212
ID de substance PubChem :
24899564
Nomenclature NACRES :
NA.25

Niveau de qualité

100

Pureté

≥98%

Forme

liquid

Couleur

light yellow

Indice de réfraction

n20/D 1.494 (lit.)

Point d'ébullition

285 °C/25 mmHg (lit.)

Pf

−75 °C (lit.)

Densité

0.858 g/mL at 25 °C (lit.)

Application(s)

metabolomics
vitamins, nutraceuticals, and natural products

Température de stockage

2-8°C

Chaîne SMILES 

CC(C)=CCCC(C)=CCCC(C)=CCC\C=C(/C)CCC=C(C)CCC=C(C)C

InChI

1S/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24+

Clé InChI

YYGNTYWPHWGJRM-AAJYLUCBSA-N

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Catégories apparentées

Description générale

Squalene is a hydrocarbon containing double bond commonly found in shark liver oil. It is also present in vegetable oils but to a lesser extent.

Application

Squalene has been used:
  • as a standard for lipid identification and quantification
  • in the isolation of macrophages for parasite incubation
  • as a standard for the quantification of squalene in squalene analysis of oil samples

Actions biochimiques/physiologiques

Squalene is a biosynthetic precursor to all steroids. It acts as a cytoprotective agent to normal cells exposed to carcinogens and antitumor agents. Squalene helps in equalizing the blood cholesterol levels. It increases the production of HDL (high density lipoprotein) and the excretion of LDL (low density lipoprotein). This helps in reducing the risk of heart disease and protects the less stable body fats from oxidation. It is also used in treating hypercholesterolemia. Squalene is known to improve the efficiency of cholesterol lowering drugs. It also serves as an antioxidant by preventing the effects of free radical. It protects skin from drying and other environmental conditions such as oxidation, ultraviolet rays and pollutants. Squalene is known to promote wound healing.

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H304

Classification des risques

Asp. Tox. 1

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Zih-rou Huang et al.
Acta pharmacologica Sinica, 29(9), 1094-1102 (2008-08-23)
Camptothecin is an anticancer drug that acts against a broad spectrum of tumors. The clinical application of camptothecin is limited by its insolubility, instability, and toxicity problems. The aim of this study was to develop and characterize lipid nanoparticles with
Reduced skin barrier function parallels abnormal stratum corneum lipid organization in patients with lamellar ichthyosis
Lavrijsen APM, et al.
The Journal of Investigative Dermatology, 105(4), 619-624 (1995)
Rainbow trout leucocyte activity: influence on the ectoparasitic monogenean Gyrodactylus derjavini
Buchmann K and Bresciani J
Diseases of Aquatic Organisms, 35(1), 13-22 (1999)
Influence of the addition of Amaranthus mantegazzianus flour on the nutritional and health properties of pasta
Martinez CS, et al.
Cogent Food & Agriculture, 2(1), 1136097-1136097 (2016)
The Palm Oil Miracle, 63-63 (2007)
Afficher tous les articles scientifiques apparentés

Articles

Dietary Terpenes

Terpenes comprise the largest and most diverse class of secondary metabolites; approximately 55,000 compounds have been identified to date.

Cholesterol Biosynthesis

Biosynthesis of cholesterol generally takes place in the endoplasmic reticulum of hepatic cells and begins with acetyl- CoA, which is mainly derived from an oxidation reaction in the mitochondria. Acetyl-CoA and acetoacetyl-CoA are converted to 3-hydroxy- 3-methylglutaryl-CoA (HMG-CoA) by HMG-CoA synthase.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique