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RES0114M-A7

SAFC

MES sodium salt

Synonyme(s) :

Acide 2-(N-morpholino)éthanesulfonique sodium salt, Acide 4-morpholinoéthanesulfonique sodium salt

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About This Item

Formule empirique (notation de Hill):
C6H12NNaO4S
Numéro CAS:
71119-23-8
Poids moléculaire :
217.22
Numéro Beilstein :
3765682
Numéro CE :
275-203-2
Numéro MDL:
MFCD00065473
Code UNSPSC :
12161700
Nomenclature NACRES :
NA.21

Source biologique

synthetic

Forme

powder

Technique(s)

cell culture | mammalian: suitable

Impuretés

Endotoxin and microbial, tested

Plage de pH utile

5.5-6.7

pKa  

6.1

Adéquation

suitable for manufacturing use

Activité étrangère

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

Chaîne SMILES 

[Na+].[O-]S(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1

Clé InChI

IRHWMYKYLWNHTL-UHFFFAOYSA-M

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Catégories apparentées

Description générale

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Application

MES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

MES Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Conditionnement

Product is available in the following package sizes:
RES0114M-A701X: 100g container
RES0114M-A702X 1kg container
RES0114M-A704X: 10kg container
RES0114M-A705X: 25kg container

Informations légales

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Remplacé(e)(s) par

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Elisabet Fuguet et al.
Electrophoresis, 29(13), 2841-2851 (2008-06-12)
The performance of the most common and also some other less common CE buffers has been tested for the pKa determination of several types of compounds (pyridine, amines, and phenols). The selected buffers cover a pH ranging from 3.7 to
Cecilia Gelfi et al.
Electrophoresis, 23(10), 1517-1523 (2002-07-13)
A large number of point mutations in the p53 gene have been detected by capillary zone electrophoresis via single-strand conformation polymorphism (SSCP) analysis. A much improved detection sensitivity was obtained via the following modifications in running conditions: use of low-viscosity
Padmavati Venkataraman et al.
The Journal of biological chemistry, 280(22), 21463-21472 (2005-03-24)
The influenza virus M2 proton-selective ion channel activity facilitates virus uncoating, a process that occurs in the acidic environment of the endosome. The M2 channel causes acidification of the interior of the virus particle, which results in viral protein-protein dissociation.
Taras P Pasternak et al.
Plant physiology, 129(4), 1807-1819 (2002-08-15)
Culturing leaf protoplast-derived cells of the embryogenic alfalfa (Medicago sativa subsp. varia A2) genotype in the presence of low (1 microM) or high (10 microM) 2, 4-dichlorophenoxyacetic acid (2,4-D) concentrations results in different cell types. Cells exposed to high 2,4-D
Christian Engelbrekt et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 11(13), 2844-2853 (2010-08-18)
Monodisperse platinum nanoparticles (PtNPs) were synthesized by a green recipe. Glucose serves as a reducing agent and starch as a stabilization agent to protect the freshly formed PtNP cores in buffered aqueous solutions. Among the ten buffers studied, 2-(N-morpholino)ethanesulfonic acid
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