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Principaux documents

P8791

Sigma-Aldrich

Polyglycine

mol wt 500-5,000

Synonyme(s) :

Glycine homopolymer

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352202
eCl@ss :
32160406
ID de substance PubChem :
Nomenclature NACRES :
NA.26

Forme

lyophilized powder

Niveau de qualité

Poids mol.

500-5,000

Couleur

white to light yellow

Pf

300 °C

Température de stockage

−20°C

Chaîne SMILES 

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

Clé InChI

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Informations sur le gène

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Application

Polyglycine has been used as an external intensity standard for measuring cross polarization (CP) nuclear magnetic resonance (NMR) spectrum measurements and ion mobility mass spectrometry. It is suitable for use as a model for UV resonance Raman spectroscopy studies.

Actions biochimiques/physiologiques

Polyglycine exists in two forms, namely the polyglycine I (PGI) with anti-parallel β-sheet structure and polyglycine II (PGII) with extended 31-helix. It is a most flexible polypeptide with minimal steric hindrance and its solubility increases in the presence of lithium ions. It is present in mammals and plants. Polyglycine stretch associated with the chloroplast membrane protein, Toc5 is essential for envelop sorting.

Notes préparatoires

Prepared by phosphorylation.

Autres remarques

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Kiran Kumar Morishetti et al.
Journal of the American Society for Mass Spectrometry, 21(4), 603-614 (2010-01-29)
The sequence and conformational effects on the gas-phase acidities of peptides have been studied by using two pairs of isomeric cysteine-polyglycine peptides, CysGly(3,4)NH(2) and Gly(3,4)CysNH(2). The extended Cooks kinetic method was employed to determine the gas-phase acidities using a triple
Sergei Bykov et al.
The journal of physical chemistry. B, 114(19), 6636-6641 (2010-04-27)
Polyglycine (polygly) is an important model system for understanding the structural preferences of unfolded polypeptides in solution. We utilized UV resonance and visible Raman spectroscopy to investigate the conformational preferences of polygly peptides of different lengths in water containing LiCl
Solid-state 15 N NMR analysis of highly 15 N-enriched plant materials
Smernik RJ and Baldock JA
Plant and Soil, 275(1-2), 271-283 (2005)
Nicola J Rutherford et al.
Neurobiology of aging, 33(2), 424-424 (2010-11-16)
Insertion and deletion variants (indels) within poly glycine tracts of fused in sarcoma (FUS) were initially reported as causative of disease in amyotrophic lateral sclerosis (ALS). Subsequent studies identified similar indels in controls and suggested that these indels may confer
Dahiyana Cristancho et al.
The Journal of chemical physics, 132(6), 065102-065102 (2010-02-16)
Molecules that resemble a semiconductor diode depletion zone are those with an intrinsic electric dipole, which were suggested as potential electronic devices. However, so far, no single molecule has met such a goal because any electron donor-acceptor linker strongly diminishes

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