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N217

Sigma-Aldrich

Anti-Nitric Oxide Synthase, Universal antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

Numéro MDL:
MFCD01324876
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

mouse, bovine, rat, human, pig

Technique(s)

immunohistochemistry (frozen sections): 1:100
western blot: 1:1,000

Numéro d'accès UniProt

P29474

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... NOS1(4842) , NOS2(4843) , NOS3(4846)
mouse ... Nos1(18125) , Nos2(18126)
rat ... Nos1(24598) , Nos2(24599)

Immunogène

synthetic peptide (Asp-Gln-Lys-Arg-Tyr-His-Glu-Asp-Ile-Phe-Gly), derived from amino acids 1113-1122 with N-terminally added Asp, of mouse iNOS and nNOS. The immunogen sequence is highly conserved among the various NOS isoforms.

Forme physique

Solution in phosphate buffered saline, containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Description
Tarif

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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K Somersalo et al.
The Journal of biological chemistry, 270(15), 8629-8636 (1995-04-14)
Intracellular adhesion molecule-2 (ICAM-2), one of the ligands of CD11a/CD18 (LFA-1), is mainly expressed on endothelial and hematopoietic cells. The biological significance of ICAM-2 has remained unclear. Previous findings have shown that a peptide from ICAM-2, spanning residues 21-42 from
L L Thomsen et al.
Cancer research, 54(5), 1352-1354 (1994-03-01)
Nitric oxide is generated by the NO synthases, a family of isoenzymes expressed in a wide range of mammalian cells. In the vascular and nervous systems distinct isoforms generate NO to act as a signal transduction mechanism. The isoform induced
Sumiharu Nagaoka et al.
Insect biochemistry and molecular biology, 84, 40-47 (2017-04-18)
A trypsin-like protease called initiatorin is known to initiate sperm motility in the silkworm, Bombyx mori, but little is known about the signaling events leading to sperm flagellar beating. The aim of this study was to investigate whether this mechanism
A Amaroli et al.
European journal of histochemistry : EJH, 56(4), e47-e47 (2013-01-31)
In Dictyostelium discoideum (D. discoideum), compounds generating nitric oxide (NO) inhibit its aggregation and differentiation without altering cyclic guanosine monophosphate (cGMP) production. They do it by preventing initiation of cyclic adenosine monophosphate (cAMP) pulses. Furthermore, these compounds stimulate adenosine diphosphate

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