MAK530

Alkaline Phosphatase (ALP) Assay Kit

sufficient for 100 fluorometric tests

• Synonyme(s) : Fluorometric Alkaline Phosphatase Assay Kit
• Code UNSPSC : 12161503
• Nomenclature NACRES : NA.84

Propriétés

• Niveau de qualité: 100
• Application(s): pharmaceutical
• Méthode de détection: fluorometric
• Maladie(s) pertinente(s): cancer; neurological disorders; gastrointestinal diseases; genitourinary disorders
• Conditions d'expédition: wet ice
• Température de stockage: −20°C

Description

Description générale

Alkaline phosphatase (ALP) catalyzes the hydrolysis of phosphate esters in an alkaline environment, resulting in the formation of an organic radical and inorganic phosphate. In mammals, this enzyme is found mainly in the liver and bones. Marked increase in serum ALP levels, a disease known as hyperalkalinephosphatasemia, has been associated with malignant biliary obstruction, primary biliary cirrhosis, primary sclerosing cholangitis, hepatic lymphoma and sarcoidosis.

Caractéristiques et avantages

• Detection limit of 0.02 U/L
• Compatible with high-throughput handling systems.

Adéquation

The kit is suitable for ALP activity in serum, plasma and other sources, characterization and quality control for ALP production, and for high-throughput screening for ALP modulators.

Principe

The Alkaline Phosphatase (ALP) Assay Kit utilizes 4-methylumbelliferyl phosphate that is hydrolyzed by ALP into the highly fluorescent product 4methylumbelliferone. The rate of the fluorescence increase is directly proportional to the enzyme activity.

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H318
• Conseils de prudence: P280 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1