MAK110
MTP Activity Assay Kit
Supplied by Roar Biomedical, Inc.
Synonyme(s) :
MTTP Activity Assay Kit, Microsomal triglyceride transfer protein activity assay kit
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
About This Item
Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84
Produits recommandés
Utilisation
sufficient for 100 fluorometric tests
Application(s)
pharmaceutical
Méthode de détection
fluorometric
Maladie(s) pertinente(s)
cardiovascular diseases
Température de stockage
2-8°C
Informations sur le gène
human ... MTTP(4547)
Description générale
Microsomal triglyceride transfer protein (MTP), a membrane-bound protein present in the liver, plays an important role in the assembly and secretion of very low density lipoprotein (VLDL). MTP is also necessary for assembly and secretion of chylomicrons by the intestine. This protein facilitates the transfer of triglyceride (TG), cholesteryl ester (CE) and phosphatidylcholine (PC) between phospholipid surfaces. Mutation in the MTP gene leads to abetalipoproteinemia.
Application
MTP Activity Assay Kit has been used to measure the activity of microsomal triglyceride transfer protein (MTP).
Caractéristiques et avantages
Compatible with high-throughput handling systems.
Adéquation
Suitable for measuring microsomal [triglyceride] transfer protein (MTP) activity in cell lysates or tissue homogenates, or for screening MTP activity inhibitors.
Principe
The MTP Activity Assay Kit is a sensitive, homogeneous fluorometric assay useful for continuous measurement of MTP activity in cell lysate or tissue homogenate. This kit includes proprietary substrates that enable the detection of MTP-mediated transfer of neutral lipid. The transfer activity results in an increase in fluorescence intensity (λEx=465 nm/λEm=535 nm).
Remarque sur l'analyse
En option
Réf. du produit
Description
Tarif
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Code de la classe de stockage
10 - Combustible liquids
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Les clients ont également consulté
Jessica Wagoner et al.
Hepatology (Baltimore, Md.), 51(6), 1912-1921 (2010-06-01)
Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo. In the current study, we further characterized silymarin's antiviral actions. Silymarin
Jonathan Goldwasser et al.
Journal of hepatology, 55(5), 963-971 (2011-03-01)
Hepatitis C virus (HCV) infection affects 3% of the world population and is the leading cause of chronic liver disease worldwide. Current standard of care is effective in only 50% of the patients, poorly tolerated, and associated with significant side
Short-term palmitate supply impairs intestinal insulin signaling via ceramide production.
Tran T T T, et al.
The Journal of Biological Chemistry, M115-M115 (2016)
J Estellé et al.
Animal genetics, 40(6), 813-820 (2009-06-06)
Despite the economic interest of the fatty acid profile in pigs, no gene has been convincingly associated with this trait so far. Here, the porcine microsomal triglyceride transfer protein (MTTP) gene, which plays a crucial role in the assembly of
Yuan-Lung Cheng et al.
Clinical science (London, England : 1979), 125(9), 439-448 (2013-05-11)
HCV (hepatitis C virus) infection affects an estimated 180 million people in the world's population. Adverse effects occur frequently with current standard treatment of interferon and ribavirin, while resistance of new direct anti-viral agents, NS3 protease inhibitors, is a major
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique