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Key Documents

M9434

Sigma-Aldrich

Anti-Myelin Basic Protein Antibody

rat monoclonal, 14

Synonyme(s) :

Anti-MBP

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

product name

Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat, clone 14, tissue culture supernatant

Source biologique

rat

Niveau de qualité

Conjugué

unconjugated

Forme d'anticorps

tissue culture supernatant

Type de produit anticorps

primary antibodies

Clone

14, monoclonal

Contient

0.09% sodium azide

Espèces réactives

horse, chicken, human

Technique(s)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

Isotype

IgG

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... MBP(4155)

Description générale

Myelin basic protein (MBP) is part of the myelin sheath and is a calcium-dependent protein. It has six isoforms and the gene encoding it is localized on human chromosome 18q23.

Spécificité

Recognizes amino acids 36-50 of myelin basic protein.

Immunogène

bovine myelin basic protein.

Actions biochimiques/physiologiques

Myelin basic protein (MBP) associates with calmodulin and has been identified as an auto-antigen in multiple sclerosis (MS). It also inhibits the assembly of amyloid-β protein.

Notes préparatoires

Generated by somatic cell hybridization of NS0 myeloma cells with spleen cells from an outbred rat immunized with bovine myelin basic protein.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids


Certificats d'analyse (COA)

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