M076000

Sulfur 42

• Synonyme(s) : Phenyl-3H-1,2,4-dithiazol-3-one
• Formule empirique (notation de Hill): C₈H₅NOS₂
• Numéro CAS: 7047-10-1
• Poids moléculaire : 195.26
• Numéro MDL: MFCD02311276
• Code UNSPSC : 12352200
• ID de substance PubChem : 329817828
• Nomenclature NACRES : NA.03

Propriétés

• Type: for DNA synthesis
• Niveau de qualité: 200
• Gamme de produits: Proligo Reagents
• Pureté: ≥99.0% (reversed phase HPLC)
• Forme: solid
• Conditionnement: pkg of 1 g M076000-1G; 2 g of 2 g M076000-2G
• Impuretés: ≤0.1% water content (Karl Fischer)
• Couleur: faintly yellow to yellow
• Solubilité: acetonitrile: 0.1 M, clear
• Adéquation: conforms to structure for H-NMR
• Température de stockage: 2-8°C
• Chaîne SMILES: O=C1SSC(C2=CC=CC=C2)=N1
• InChI: 1S/C8H5NOS2/c10-8-9-7(11-12-8)6-4-2-1-3-5-6/h1-5H
• Clé InChI: LKDWQHQNDDNHSC-UHFFFAOYSA-N

Description

Description générale

Sulfur 42 is a sulfurization reagent.

Application

Sulfur 42 is suitable for use instead of an Oxidizer during the synthesis cycle to manufacture thioated oligonucleotides.

Caractéristiques et avantages

• Sulfur 42 is at least 4 times more reactive than Beaucage reagent or PADS
• Crystalline powder
• Odourless, no foul smell
• Solubility in ACN up to 0.28M at (+10 °C); no need to applied a co-solvent like in DCM, THF
• The solvent for the dissolution of the reagent should be dry (< 50 ppm) in order to minimize P=O impurities
• Stable in ACN solution for at least 21 days
• Recommended reaction time for the sulfurization in oligonucleotide synthesis for a 0.1M solution is 60 sec

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable