GW22757
Anti-AKT1 (ab1) antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
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About This Item
Source biologique
chicken
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Forme
buffered aqueous solution
Espèces réactives
rat, human, mouse
Fabricant/nom de marque
Genway 15-288-22757
Technique(s)
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... AKT1(207)
Catégories apparentées
Immunogène
Immunogen Sequence: GI # 62241011, sequence 2-200
Recombinant serine/threonine protein kinase
Application
Anti-AKT1 (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Actions biochimiques/physiologiques
RAC-α serine/threonine-protein kinase is an enzyme encoded by the AKT1 gene in humans and is a member of the serine/threoine AGC protein kinase family. It is an intracellular signal transduction protein activated by growth hormones and its pathway is critically involved in cancer cell growth, proliferation, metabolism, invasion and survival. AKT1 acts as a potential target for cancer gene therapy. The gene is frequently activated in a variety of cancer types and is accepted as a promising anticancer therapeutic target.
Forme physique
Solution in phosphate buffered saline containing 0.02% sodium azide.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Réf. du produit
Description
Tarif
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Min Zhang et al.
Clinical laboratory, 60(1), 1-8 (2014-03-08)
AKT1 is a member of the serine/threoine AGC protein kinase family involved in cancer's metabolism, growth, proliferation, and survival. It is a potential target for cancer gene therapy. In the present study, we used DNAzyme and siRNA technology to inhibit
F Yang et al.
Cell death & disease, 5, e1114-e1114 (2014-03-15)
The serine/threonine kinase AKT is generally accepted as a promising anticancer therapeutic target. However, the relief of feedback inhibition and enhancement of other survival pathways often attenuate the anticancer effects of AKT inhibitors. These compensatory mechanisms are very complicated and
Prognostic significance of protein kinase B/Akt pathway in patients with non-small cell lung cancer.
Alpaslan Mayadagli et al.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 19(1), 157-163 (2014-03-25)
Akt, also known as protein kinase B (PKB), is an intracellular signal transduction protein activated by growth hormones. PKB/Akt is frequently activated in a variety of cancer types, but its role in the development and progression of lung cancer has
Xiaoting Wang et al.
Journal of cancer research and clinical oncology, 140(8), 1399-1411 (2014-04-17)
v-akt Murine thymoma viral oncogene homolog (AKT) pathway is critically involved in cancer cell growth, invasion, and survival. We examined the correlation between the genetic variations in molecules of AKT pathway and clinical outcomes of gastric cancer. Six single nucleotide
Mariëtte E G Kranendonk et al.
Obesity (Silver Spring, Md.), 22(10), 2216-2223 (2014-07-22)
Insulin resistance (IR) is a key mechanism in obesity-induced cardiovascular disease. To unravel mechanisms whereby human adipose tissue (AT) contributes to systemic IR, the effect of human AT-extracellular vesicles (EVs) on insulin signaling in liver and muscle cells was determined.
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