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Key Documents

G5875

Sigma-Aldrich

α-D-Glucose 1,6-bisphosphate tetra(cyclohexylammonium) salt hydrate

≥95% dry basis

Synonyme(s) :

α-D-Glucose 1,6-diphosphate tetra(cyclohexylammonium) salt hydrate, Glc-1,6-PP.4CHA

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About This Item

Formule empirique (notation de Hill):
C6H14O12P2 · 4C6H13N · xH2O
Numéro CAS:
Poids moléculaire :
736.81 (anhydrous basis)
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352201
ID de substance PubChem :
Nomenclature NACRES :
NA.25

Source biologique

synthetic

Niveau de qualité

Pureté

≥95% dry basis

Forme

powder

Couleur

white

Solubilité

water: 50 mg/mL, clear, colorless to very faintly yellow

Température de stockage

−20°C

Chaîne SMILES 

[H]O[H].NC1CCCCC1.NC2CCCCC2.NC3CCCCC3.NC4CCCCC4.O[C@H]5[C@H](O)[C@@H](COP(O)(O)=O)O[C@H](OP(O)(O)=O)[C@@H]5O

InChI

1S/4C6H13N.C6H14O12P2.H2O/c4*7-6-4-2-1-3-5-6;7-3-2(1-16-19(10,11)12)17-6(5(9)4(3)8)18-20(13,14)15;/h4*6H,1-5,7H2;2-9H,1H2,(H2,10,11,12)(H2,13,14,15);1H2/t;;;;2-,3-,4+,5-,6-;/m....1./s1

Clé InChI

DMUBREKUECBHKK-KMWDTYPGSA-N

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Application

Glucose-1,6-bisphosphate and fructose-1,6-bisphosphate were used as bisphosphorylated glycan standards in mass spectrometry analysis to determine if pyrophosphate ions observed in lipid A from Gram-negative bacteria were artifacts produced by condensation of two phosphate groups in the dissociating ion. α-D-Glucose 1,6-bisphosphate is used in the identification, differentiation and characterization of α-phosphoglucomutase(s), β-phosphoglucomutas(s) and α- and β-hexoglucomutase(s).
a-D-Glucose 1,6-bisphosphate is used in the identification, differentiation and characterization of a-phosphoglucomutase(s), ß-phosphoglucomutase(s) and a- and ß-hexoglucomutase(s).

Actions biochimiques/physiologiques

Glucose-1,6-bisphosphate and fructose-1,6-bisphosphate were used as bisphosphorylated glycan standards in mass spectrometry analysis to determine if pyrophosphate ions observed in lipid A from Gram-negative bacteria were artifacts produced by condensation of two phosphate groups in the dissociating ion.
Metabolite formed via the activity of Glucose-1,6-biphosphate synthase. Glucose-1,6-biphosphate (G-1,6-BP) acts as an inhibitor of hexokinase function and an activator of phosphofructokinase-1 and pyruvate kinase. G-1,6-BP also acts as a coenzyme for phosphoglucomutate and a cofactor for phosphopentomutase.

Qualité

Synthetic

Autres remarques

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Jace W Jones et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(35), 12742-12747 (2008-08-30)
Lipid A isolated from several bacteria (Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica, and various strains of Yersinia) showed abundant formation of pyrophosphate anions upon ion dissociation. Pyrophosphate [H(3)P(2)O(7)](-) and/or [HP(2)O(6)](-) anions were observed as dominant fragments from diphosphorylated lipid A

Protocoles

This procedure may be used for all Phosphoglucomutase products except for Phosphoglucomutase, Catalog Number P4109.

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