G5419
Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody produced in mouse
clone K-87, purified antibody
Synonyme(s) :
Anti-GAD 67
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About This Item
Produits recommandés
Source biologique
mouse
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
purified antibody
Type de produit anticorps
primary antibodies
Clone
K-87, monoclonal
Poids mol.
antigen 67 kDa
Espèces réactives
rat, mouse, human
Concentration
~1 mg/mL
Technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:20,000 (with antigen-retrieval step)
western blot: 1:500-1:20,000 using mouse brain extract
Isotype
IgG1κ
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Température de stockage
−70°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... GAD1(2571)
mouse ... Gad1(14415)
rat ... Gad1(24379)
Description générale
Glutamic Acid Decarboxylase 67 (GAD67) is encoded by the gene glutamic acid decarboxylase 1 (GAD1). GAD1 gene is located on the human chromosome at 2q31.1. GAD67 is localized in the dendrites and cell bodies.
Spécificité
Reacts specifically with GAD67. Does not crossreact with GAD65.
Immunogène
This peptide does not share homology with GAD65.
synthetic peptide from mouse GAD67 (amino acids 87-106).
Application
Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody is suitable for use in immunoblot, western blot (at 1:500-1:20,000 dilutions using mouse brain extract) and immunohistochemistry (at 1:500-1:20,000 dilutions in mouse brain sections).
Monoclonal anti-glutamic acid decarboxylase 67 (GAD67) antibody produced in mouse has been used in:
- immunohistofluorescence
- western blotting
- immunohistochemistry.
Actions biochimiques/physiologiques
Glutamic Acid Decarboxylase 67 (GAD67) is involved in the production of γ-amino butyric acid (GABA), a inhibitory neurotransmitter in the central nervous system (CNS). Deficiency of GAD67 leads to psychosis, schizophrenia and bipolar diseases.
Forme physique
Solution in phosphate buffered saline containing 0.01% sodium azide.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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