G5417

Glycine

• Synonyme(s) : Acide aminoacétique, Acide aminoéthanoïque, Glycocolle
• Formule linéaire : NH₂CH₂COOH
• Numéro CAS: 56-40-6
• Poids moléculaire : 75.07
• Numéro Beilstein : 635782
• Numéro CE : 200-272-2
• Numéro MDL: MFCD00008131
• Code UNSPSC : 12352209
• eCl@ss : 32160406
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: non-animal source
• Niveau de qualité: 400
• Pureté: ≥98.5%
• Forme: crystalline powder
• Technique(s): cell culture | mammalian: suitable
• Impuretés: endotoxin, heavy metals, trace metals, residual solvents, tested
• pH: 5.9-6.4
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• Pf: 240 °C (dec.) (lit.)
• Solubilité: H₂O: 100 mg/mL
• Absorption UV: λ: 260 nm A_max: ≤0.04; λ: 260 nm A_max: -0.006; λ: 280 nm A_max: ≤0.04; λ: 280 nm A_max: -0.003
• Adéquation: suitable for manufacturing use
• Application(s): pharmaceutical (small molecule)
• Activité étrangère: cytotoxicity, tested
• Chaîne SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Clé InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Informations sur le gène: rat ... Grin2a(24409)

Description

Description générale

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

To request the documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Application

Glycine is a non-essential amino acid. It is the simplest of the amino acids and plays various roles in biology. It is structurally unique among the biological amino acids in that it does not have an asymmetric center, and thus is not chiral. It is commonly used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Actions biochimiques/physiologiques

Neurotransmetteur inhibiteur de la moelle épinière, régulateur allostérique des récepteurs du NMDA.

Informations légales

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)