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C0742

CKI-7 dihydrochloride

Name: CKI-7 dihydrochloride
Brand: SIGMA

≥98% (HPLC), solid, CK1 inhibitor

Synonyme(s) :

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride

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About This Item

Formule empirique (notation de Hill):

C₁₁H₁₂ClN₃O₂S · 2HCl

Numéro CAS:

1177141-67-1

Poids moléculaire :

358.67

Numéro MDL:

MFCD00897689

Code UNSPSC :

12352200

ID de substance PubChem :

24724430

Nomenclature NACRES :

NA.77

product name

CKI-7 dihydrochloride, ≥98% (HPLC), solid

Pureté

≥98% (HPLC)

Forme

solid

Conditions de stockage

desiccated

Couleur

white to light tan

Solubilité

H₂O: >5 mg/mL

Température de stockage

−20°C

Chaîne SMILES

Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

InChI

1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H

Clé InChI

JUAVTXYOCISSSL-UHFFFAOYSA-N

Actions biochimiques/physiologiques

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC₅₀ = 6 μM.

Attention

Material is hygroscopic

Pictogrammes

GHS06

Mention d'avertissement

Danger

Mentions de danger

H301

Conseils de prudence

P264 - P270 - P301 + P310 - P405 - P501

Classification des risques

Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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