B1436

BAX Inhibiting Peptide V5

≥97% (HPLC), lyophilized powder

• Synonyme(s) : BIP-V5
• Formule empirique (notation de Hill): C₂₇H₅₀N₆O₆S
• Numéro CAS: 579492-81-2
• Poids moléculaire : 586.79
• Numéro MDL: MFCD04974826
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Niveau de qualité: 200
• Pureté: ≥97% (HPLC)
• Forme: lyophilized powder
• Température de stockage: −20°C
• InChI: 1S/C27H50N6O6S/c1-16(2)15-20(24(35)31-19(27(38)39)9-6-7-12-28)32-23(34)18(11-14-40-5)30-25(36)21-10-8-13-33(21)26(37)22(29)17(3)4/h16-22H,6-15,28-29H2,1-5H3,(H,30,36)(H,31,35)(H,32,34)(H,38,39)/t18-,19-,20-,21-,22-/m0/s1
• Clé InChI: NHMUTADCTDDWPV-YFNVTMOMSA-N

Description

Amino Acid Sequence

Val-Pro-Met-Leu-Lys

Actions biochimiques/physiologiques

BAX Inhibiting Peptide V5 protects Bax against conformational changes and it also prevents mitochondrial translocation. In vitro analysis prove that peptide V5 prevents apoptosis, mediated by a number of agents including staurosporine, ultraviolet and anti-cancer drug.

Bax-mediated apoptosis inhibitor; membrane permeable pentapeptide based on the Ku70-Bax inhibiting domain.

Autres remarques

Lyophilized from 0.1% TFA in H2O

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)