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Merck
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86C

Sigma-Aldrich

Leukocyte Alkaline Phosphatase Kit

based on naphthol AS-BI and fast blue BB salt

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About This Item

Code UNSPSC :
12352106
eCl@ss :
42010105
Nomenclature NACRES :
NA.47

Niveau de qualité

500

Durée de conservation

Expiry date on the label.

IVD

for in vitro diagnostic use

Application(s)

hematology
histology

Conditions d'expédition

wet ice

Température de stockage

2-8°C

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Catégories apparentées

Application

Leukocyte Alkaline Phosphatase (LAP) kits are intended for the qualitative demonstration of alkaline phosphatase activity in white blood cells.
Peripheral blood or bone marrow preparations are fixed to a microscope slide. The film is then incubated in a mixture of naphthol AS-BI alkaline solution with fast blue BB. The resulting insoluble diffuse, blue dye deposit indicates sites of alkaline phosphatase activity.

Composants de kit seuls

Réf. du produit
Description
  • Citrate Solution (915) 50 mL
  • FBB-Alkaline Solution (863) 10 mL
  • Naphthol AS-BI Alkaline Solution (861) 10 mL
  • Neutral Red Solution (N6264) 50 mL
  • Sodium Nitrite Solution (914) 10 mL

Pictogrammes

Skull and crossbonesCorrosionEnvironment
GHS06,GHS05,GHS09

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1C - Skin Sens. 1 - STOT SE 3

Organes cibles

Respiratory system

Risques supp

EUH071

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Barbara Klotz et al.
PloS one, 7(1), e29959-e29959 (2012-01-14)
1,25-dihydroxyvitamin D3 (1,25D3) was reported to induce premature organismal aging in fibroblast growth factor-23 (Fgf23) and klotho deficient mice, which is of main interest as 1,25D3 supplementation of its precursor cholecalciferol is used in basic osteoporosis treatment. We wanted to
Gregory M Cooper et al.
Tissue engineering. Part A, 16(5), 1749-1759 (2009-12-24)
The purpose of this study was to demonstrate spatial control of osteoblast differentiation in vitro and bone formation in vivo using inkjet bioprinting technology and to create three-dimensional persistent bio-ink patterns of bone morphogenetic protein-2 (BMP-2) and its modifiers immobilized
Julia Dotterweich et al.
PloS one, 11(5), e0155087-e0155087 (2016-05-10)
Multiple myeloma is one of the most common hematological diseases and is characterized by an aberrant proliferation of plasma cells within the bone marrow. As a result of crosstalk between cancer cells and the bone microenvironment, bone homeostasis is disrupted
Ming-Tzu Tsai et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 27(9), 1169-1174 (2009-03-11)
Human mesenchymal stem cells (hMSCs) are a promising candidate cell type for regenerative medicine and tissue engineering applications by virtue of their capacity for self-renewal and multipotent differentiation. Our intent was to characterize the effect of pulsed electromagnetic fields (PEMFs)
Sandra Bermeo et al.
Journal of cellular biochemistry, 118(12), 4425-4435 (2017-04-28)
Mutations in MAN1, a protein of the nuclear envelope, cause bone phenotypes characterized by hyperostosis. The mechanism of this pro-osteogenic phenotype remains unknown. We increased and decreased MAN1 expression in mesenchymal stem cells (MSC) upon which standard osteogenic and adipogenic
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