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Key Documents

380R-1

Sigma-Aldrich

Arginase-1 (SP156) Rabbit Monoclonal Antibody

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About This Item

Code UNSPSC :
12352204
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

culture supernatant

Type de produit anticorps

primary antibodies

Clone

SP156, monoclonal

Description

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL concentrate (380R-14)
vial of 0.5 mL concentrate (380R-15)
bottle of 1.0 mL predilute (380R-17)
vial of 1.0 mL concentrate (380R-16)
bottle of 7.0 mL predilute (380R-18)

Fabricant/nom de marque

Cell Marque™

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

Isotype

IgG

Contrôle

hepatocellular carcinoma, normal liver

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Visualisation

cytoplasmic, nuclear

Informations sur le gène

human ... ARG1(383)

Description générale

Arginase is a key metalloenzyme of the urea cycle responsible for the hydrolysis of L-arginine to L-ornithine and urea. Two main isoforms exist, arginase-1 and arginase-2, encoded by different genes and with different tissue distributions. The arginase-1 isoform is a cytosolic protein that is produced by normal liver tissue and is typically expressed in hepatocellular carcinoma. Arginase-1 (SP156) is used as an immunohistochemical marker to aid in the identification of hepatocellular carcinoma.

Qualité


IVD
IVD
IVD
RUO

Liaison

Arginase-1 Positive Control Slides, Product No. 380S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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A Wee
Cytopathology : official journal of the British Society for Clinical Cytology, 22(5), 287-305 (2011-07-19)
The role of fine needle aspiration (FNA) biopsy of the liver has evolved. Advances in imaging modalities have obviated the need for tissue confirmation in clinically classic hepatocellular carcinoma (HCC). The risks of needle tract seeding and haematogenous dissemination have
H B el-Serag
Clinics in liver disease, 5(1), 87-107 (2001-02-24)
The epidemiology of hepatocellular carcinoma (HCC) is characterized by marked differences between genders, ethnic groups, and geographic regions. These variations are explained by the nature, frequency, and time of acquisition of the major risk factors for cirrhosis--namely hepatitis B virus
Z W Zhu et al.
Gut, 48(4), 558-564 (2001-03-15)
Hepatocellular carcinoma (HCC) is a common malignant tumour worldwide, and its differential diagnosis from benign lesions of the liver is often difficult yet of great clinical importance. In the present study, we analysed whether glypican-3 is useful in differentiating between
Aileen Wee
CytoJournal, 2, 7-7 (2005-06-09)
The role of fine needle aspiration biopsy (FNAB) in the evaluation of focal liver lesions has evolved. Guided FNAB is still useful to procure a tissue diagnosis if clinical, biochemical and radiologic findings are inconclusive. Major diagnostic issues include: (i)
H Multhaupt et al.
Histochemistry, 87(5), 465-470 (1987-01-01)
Monoclonal antibodies against human liver arginase were raised in order to determine the exact distribution of arginase in human liver using a modified indirect unlabelled immunoperoxidase method. In normal human liver specific immunohistochemical staining was found in the cytoplasm of
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