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Principaux documents

298R-1

Sigma-Aldrich

Myosin, Smooth Muscle (EP166) Rabbit Monoclonal Primary Antibody

Synonyme(s) :

Smooth Muscle Myosin, heavy chain (SMM-HC)

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About This Item

Code UNSPSC :
12352203

Source biologique

rabbit

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

culture supernatant

Type de produit anticorps

primary antibodies

Clone

EP166, monoclonal

Description

For In Vitro Diagnostic Use in Select Regions

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL concentrate (298R-14)
vial of 0.1 mL concentrate Research Use Only (298R-14-RUO)
vial of 0.5 mL concentrate (298R-15)
vial of 1.0 mL concentrate (298R-16)
vial of 1.0 mL concentrate Research Use Only (298R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (298R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (298R-17)
vial of 7.0 mL pre-dilute ready-to-use (298R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (298R-18-RUO)

Fabricant/nom de marque

Cell Marque

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

Isotype

IgG

Contrôle

breast

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Visualisation

cytoplasmic

Informations sur le gène

human ... MYH11(4629)

Description générale

Smooth Muscle Myosin, heavy chain (SMM-HC) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. SMM-HC is also a myoepithelium-associated protein. Anti-SMM-HC is a monoclonal antibody to smooth muscle myosin, heavy chain that reacts with human visceral and vascular smooth muscle cells. The antibody also reacts with human myoepithelial cells. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.

Qualité


IVD

IVD

IVD

RUO

Liaison

Myosin, Smooth Muscle Positive Control Slides, Product No. 298S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Notes préparatoires

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Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Robert W Werling et al.
The American journal of surgical pathology, 27(1), 82-90 (2002-12-28)
Identification of myoepithelial cells using antibodies to cytoskeletal proteins, such as smooth muscle myosin heavy chain (SMM-HC) and calponin, can play an important role in distinguishing invasive carcinoma from its histologic mimics. However, antibodies to these proteins may also cross-react
D Lazard et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(3), 999-1003 (1993-02-01)
The expression of several differentiation markers in normal human mammary gland myoepithelium and in certain stromal fibroblasts ("myofibroblasts") associated with breast carcinomas was studied by immunofluorescence microscopy of frozen sections. Several antibodies to smooth muscle-specific proteins (smooth muscle alpha-actin, smooth

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