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Key Documents

231R-1

Sigma-Aldrich

Calponin-1 (EP798Y) Rabbit Monoclonal Primary Antibody

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

culture supernatant

Type de produit anticorps

primary antibodies

Clone

EP798Y, monoclonal

Description

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL concentrate (231R-14)
vial of 0.5 mL concentrate (231R-15)
bottle of 1.0 mL predilute (231R-17)
vial of 1.0 mL concentrate (231R-16)
bottle of 7.0 mL predilute (231R-18)

Fabricant/nom de marque

Cell Marque™

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

Isotype

IgG

Contrôle

appendix

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Visualisation

cytoplasmic

Description générale

Calponin is a 34-kD polypeptide that interacts with actin, tropomyosin, and calmodulin. Itis involved in the smooth muscle contraction mechanism and is restricted exclusively to smoothmuscle tissue. Anti-calponin has been found to be useful in staining myoepithelium and thushas been used to confirm the presence of myoepithelial cells in benign breast proliferationand their absence in invasive breast carcinomas. Calponin positivity has also been noted inmyoepithelial neoplasms and pleomorphic adenoma of the salivary gland.

Qualité


IVD
IVD
IVD
RUO

Liaison

Calponin Positive Control Slides, Product No. 231S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Consulter la Bibliothèque de documents

Antibodies to novel myoepithelium-associated proteins distinguish benign lesions and carcinoma in situ from invasive carcinoma of the breast
Wang NP, et al.
Appl. Immunohistochem., 5, 141-151 (1997)
Cheryl B Hill et al.
American journal of clinical pathology, 123(1), 36-44 (2005-03-15)
We evaluated 25 intraductal papillomas and 18 papillary carcinomas (invasive, 4; micropapillary ductal carcinoma in situ [DCIS], 5; cases originally classified as intracystic/intraductal papillary carcinoma, 9) by calponin, smooth muscle myosin heavy chain (SMM-HC), and p63 immunostains. Calponin, SMM-HC, and
J C Fanburg-Smith et al.
Human pathology, 30(11), 1336-1343 (1999-11-26)
Angiomatoid "malignant" fibrous histiocytoma (AMFH) has been considered to be a low-grade sarcoma of childhood, and, with its fibrous pseudocapsule, angiomatoid change, dense lymphoplasmacytic response, and proliferation of spindled or round cells, has been classified as a fibrohistiocytic neoplasm. We
A T Savera et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 10(11), 1093-1100 (1997-12-05)
Myoepithelial cells of salivary glands have a complex cytoskeletal immunophenotype. To elaborate the smooth muscle phenotype of salivary gland myoepithelium and to assess its contribution to the histogenesis of pleomorphic adenomas, we evaluated the immunohistochemical expression of three novel monoclonal
T Nagao et al.
Cancer, 83(7), 1292-1299 (1998-10-08)
Malignant myoepithelioma (MME) of the salivary gland, also known as myoepithelial carcinoma, is rare and its biologic behavior has not been clarified fully. Ten cases of MME were analyzed for their clinicopathologic features and immunohistochemical characteristics, focusing on prognostic factors
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