RDD029

Thiocyanate de guanidine

for molecular biology, free-flowing, Redi-Dri^™, ≥99.0%

• Synonyme(s) : Rhodanure de guanidinium, Thiocyanate de guanidinium
• Formule linéaire : NH₂C(=NH)NH₂ · HSCN
• Numéro CAS: 593-84-0
• Poids moléculaire : 118.16
• Numéro Beilstein : 3563461
• Numéro MDL: MFCD00013027
• Code UNSPSC : 12352107
• Nomenclature NACRES : NA.28

Propriétés

• Gamme de produits: Redi-Dri^™
• Niveau de qualité: 100
• Pureté: ≥99.0%
• Qualité: for molecular biology; free-flowing
• Pf: 120-122 °C (lit.)
• Activité étrangère: DNAse, none detected; RNAse, none detected
• Chaîne SMILES: SC#N.NC(N)=N
• InChI: 1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H
• Clé InChI: ZJYYHGLJYGJLLN-UHFFFAOYSA-N

Description

Description générale

Guanadine thiocyanate (GTC) is a chaotropic agent and strong denaturant that is used in research for protein degredation in vitro. This is useful for DNA or RNA isolation and purification. GTC is a key reagent for inactivation of endogenous DNases and RNase for molecular biology techniques used to isolate nucliec acids from tissues, cells, or viral genomes.

Application

Guanidine thiocyanate is commonly used for research:

• to denature proteins in cell lysis buffer
• to isolate and purify RNA from cells and tissues
• to extract DNA from cellular and viral genomes

Agent chaotrope et dénaturant fort ; solubilise les cellules.

Actions biochimiques/physiologiques

Guanadine thiocyanate is strong protein denaturant commonly combinded with phenol to lyse tissues, cells, and proteins during RNA isolation assay.

Caractéristiques et avantages

• Redi-Dri^™ makes working with hygroscopic chemicals easier
• Controls moisture and powder remains free-flowing
• Safer to handle and weigh out for routine use in lab
• Eliminates clumps and maintains product moisture and quality attributes

Autres remarques

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Informations légales

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Informations sur la sécurité

• Pictogrammes: GHS05,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H302 + H312 + H332,H314,H412
• Conseils de prudence: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 + P310
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C
• Risques supp: EUH032
• Code de la classe de stockage: 8B - Non-combustible corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable