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Key Documents

PHR1558

Supelco

Pyridine

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Pyridine

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About This Item

Formule empirique (notation de Hill):
C5H5N
Numéro CAS:
Poids moléculaire :
79.10
Numéro Beilstein :
103233
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to USP 1601747

Densité de vapeur

2.72 (vs air)

Pression de vapeur

10 mmHg ( 13.2 °C)
20 mmHg ( 25 °C)

CofA (certificat d'analyse)

current certificate can be downloaded

Température d'inflammation spontanée

899 °F

Limite d'explosivité

12.4 %

Conditionnement

ampule of 3x1.2 mL each

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Indice de réfraction

n20/D 1.509 (lit.)

Point d'ébullition

115 °C (lit.)

Pf

−42 °C (lit.)

Densité

0.978 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-30°C

Chaîne SMILES 

C1=CN=CC=C1

InChI

1S/C5H5N/c1-2-4-6-5-3-1/h1-5H

Clé InChI

JUJWROOIHBZHMG-UHFFFAOYSA-N

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Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pyridine is a heterocyclic aromatic compound that is a commonly used solvent in organic and inorganic chemistry. Its weakly basic nature allows it to act as a proton acceptor in acid base reactions, and to form salts with strong acids. In the acylation of alcohols, pyridine can act as a nucleophilic catalyst.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAC0263 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictogrammes

FlameExclamation mark

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

68.0 °F - closed cup

Point d'éclair (°C)

20 °C - closed cup


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Protocoles

GC Analysis of Class 2 Residual Solvents on OVI-G43

US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)

-Cymene; 2,5-Dimethylpyrrole; Acetoin, ≥96%, FCC, FG; 2,5-Dimethylpyrazine; 2,6-Dimethylpyrazine; 2-Ethylpyrazine, ≥98%, FG; 2,3-Dimethylpyrazine; 4-Heptanone; 3-Ethylpyridine; 2,3,5-Trimethylpyrazine; Furfural; Pyrrole; Furfuryl acetate; Linalool; Linalyl acetate; 5-Methylfurfural; γ-Butyrolactone; 2-Acetyl-1-methylpyrrole; Furfuryl alcohol; 2-Acetylpyrrole; Pyrrole-2-carboxaldehyde

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