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PHR1259

Supelco

Thiabendazole

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Thiabendazole, 2-(4-Thiazolyl)benzimidazole

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About This Item

Formule empirique (notation de Hill):
C10H7N3S
Numéro CAS:
Poids moléculaire :
201.25
Numéro Beilstein :
611403
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to Ph. Eur. T1410000
traceable to USP 1655000

Famille d'API

thiabendazole

CofA (certificat d'analyse)

current certificate can be downloaded

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-30°C

Chaîne SMILES 

c1ccc2[nH]c(nc2c1)-c3cscn3

InChI

1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)

Clé InChI

WJCNZQLZVWNLKY-UHFFFAOYSA-N

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Description générale

Thiabendazole is an orally effective broad spectrum anthelmintic and antimycotic drug with limited side-effects.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Thiabendazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and preparations by spectrophotometric, spectrofluorimetric and chromatography techniques.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA9062 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Environment

Mention d'avertissement

Warning

Mentions de danger

Conseils de prudence

Classification des risques

Aquatic Acute 1 - Aquatic Chronic 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Determination of 81 pharmaceutical drugs by high performance liquid chromatography coupled to mass spectrometry with hybrid triple quadrupole--linear ion trap in different types of water in Serbia
Petrovic M, et al.
The Science of the Total Environment, 468(2), 415-428 (2014)
Studies on the toxicologic and pharmacologic properties of thiabendazole
Robinson HJ, et al.
Toxicology and Applied Pharmacology, 7(1), 53-63 (1965)
Development of a spectrofluorimetric method for determination of thiabendazole in tablets
Kucukkolbasi S and Kilic E
Journal of Applied Pharmaceutical Science, 3(2), 19-19 (2013)
Mechanism of action of the fungicide thiabendazole, 2-(4?-thiazolyl) benzimidazole
Allen PM and Gottlieb D
Applied and Environmental Microbiology, 20(6), 919-926 (1970)
Suely R C Andrade et al.
Journal of pharmaceutical and biomedical analysis, 33(4), 655-665 (2003-11-19)
Three multivariate calibration methods, Principal Component Regression (PCR), the K-matrix method and Q-mode factor analysis followed by varimax and Imbrie's oblique rotations were applied to the simultaneous spectrophotometric determinations of mebendazole (MBZ)-cambendazole (CBZ) and thiabendazole (TBZ)-mebendazole in commercial samples of

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