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I0330000

Iopanoic acid

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2-(3-Amino-2,4,6-triiodobenzyl)butyric acid, 3-(3-Amino-2,4,6-triiodophenyl)-2-ethylpropanoic acid, Iodopanoic acid

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About This Item

Formule empirique (notation de Hill):
C11H12I3NO2
Numéro CAS:
96-83-3
Poids moléculaire :
570.93
Numéro MDL:
MFCD00038687
Code UNSPSC :
41116107
ID de substance PubChem :
329815308
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

iopanoic acid

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

O=C(O)C(CC)CC1=C(I)C(N)=C(I)C=C1I

InChI

1S/C11H12I3NO2/c1-2-5(11(16)17)3-6-7(12)4-8(13)10(15)9(6)14/h4-5H,2-3,15H2,1H3,(H,16,17)

Clé InChI

OIRFJRBSRORBCM-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Iopanoic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Piero Berti et al.
Langenbeck's archives of surgery, 392(6), 709-713 (2006-11-15)
Amiodarone-induced thyrotoxicosis is a life-threatening condition. A prompt control of thyrotoxicosis is obtained by thyroidectomy. Preparation with iopanoic acid proved to be very effective in reducing cardiovascular complications. Nevertheless, general anesthesia and extensive surgery may affect negatively patients also after
Kostja Renko et al.
Endocrinology, 153(5), 2506-2513 (2012-03-22)
Enzymatic 5'- and 5-deiodination are key reactions for local and systemic activation and inactivation of iodothyronines and thyronamines. Expression of the three deiodinase (DIO) isoenzymes is regulated by a number of parameters, including thyroid status, genotype, micronutrient availability, and disease-related
Takanori Higashino et al.
European journal of radiology, 56(1), 48-55 (2005-09-20)
To determine the clinical utility of thin-section multiplanar reformats (MPRs) from multidetector-row CT (MDCT) data sets for assessing the extent of regional tumors in non-small cell lung cancer (NSCLC) patients. Sixty consecutive NSCLC patients, who were considered candidates for surgical
Oral cholecystography with iopanoic acid.
R N Berk et al.
The New England journal of medicine, 290(4), 204-210 (1974-01-24)
Fernando Lizcano et al.
Clinical and experimental pharmacology & physiology, 35(9), 1085-1090 (2008-05-29)
To investigate the effects of iopanoic acid (IA) and carbimazole on increased activity of the hypothalamic-pituitary-adrenal (HPA) axis in hyperthyroidism, we studied 14 women with hyperthyroidism caused by Graves' disease (n + 11) or toxic multinodular goitre (n + 3)
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