C8731

Acide D-Pantothenique hemicalcium salt

meets USP testing specifications, monograph mol wt. 476.53 (C₁₈H₃₂CaN₂O₁₀)

• Synonyme(s) : (R)-(+)-N-(2,4-Dihydroxy-3,3-diméthyl-1-oxobutyl)-β-alanine hemicalcium salt, Vitamine B₅
• Formule linéaire : HOCH₂C(CH₃)₂CH(OH)CONHCH₂CH₂CO₂ ·1/2Ca
• Numéro CAS: 137-08-6
• Poids moléculaire : 238.27
• Numéro Beilstein : 3769272
• Numéro CE : 205-278-9
• Numéro MDL: MFCD00002766
• Code UNSPSC : 12352205
• eCl@ss : 34058012
• ID de substance PubChem : 24893098
• Nomenclature NACRES : NA.21

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Agence: USP/NF; meets USP testing specifications
• Forme: crystalline; powder
• Poids mol.: monograph mol wt. 476.53 (C₁₈H₃₂CaN₂O₁₀)
• Technique(s): cell culture | mammalian: suitable; cell culture | plant: suitable
• Couleur: white
• Application(s): pharmaceutical (small molecule)
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO
• InChI: 1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1
• Clé InChI: FAPWYRCQGJNNSJ-UBKPKTQASA-L

Description

Description générale

Vitamin B5 or pantothenic acid is a viscous oil that is soluble in ethanol and water. It is produced by plants and microorganisms. d-(+)pantothenic acid is the naturally occurring form of pantothenic acid and is biologically active.

Application

Calcium pantothenate has been used:

• as a component of vitamin solution for synthetic media
• as a component of vitamin mix for the ICS medium mix
• as a component of a chemically defined diet for metal depletion studies in Drosophila
• as a supplement to study coenzyme A metabolism in mouse models of non-alcoholic steatohepatitis

Précurseur dans la biosynthèse du coenzyme A.

Actions biochimiques/physiologiques

The calcium salts of panthenol are commonly used for pharmaceutical preparations. Pantothenate is a component of coenzyme A and is useful in its synthesis. Pantothenic acid is also involved in the synthesis of heme, cholesterol and fatty acids. Since vitamin B5 is found in all foods, its deficiency is not commonly observed.

Propriétés physiques

En raison du caractère instable, hygroscopique, de l′acide libre, on utilise le sel de calcium.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)