BP016

Amitriptyline hydrochloride

British Pharmacopoeia (BP) Reference Standard

• Formule empirique (notation de Hill): C₂₀H₂₃N · HCl
• Numéro CAS: 549-18-8
• Poids moléculaire : 313.86
• Numéro MDL: MFCD00012537
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: amitriptyline
• Forme: powder
• Durée de conservation: limited shelf life, expiry date on the label
• Fabricant/nom de marque: BP
• Application(s): pharmaceutical; pharmaceutical small molecule
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: Cl[H].CN(C)CC\C=C1\c2ccccc2CCc3ccccc13
• InChI: 1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H
• Clé InChI: KFYRPLNVJVHZGT-UHFFFAOYSA-N
• Informations sur le gène: human ... SLC6A2(6530) , SLC6A4(6532)

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Amitriptyline hydrochloride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Amitriptyline Oral Solution

Amitriptyline Tablets

Actions biochimiques/physiologiques

Tricyclic antidepressant; inhibits the norepinephrine and serotonin transporters with K_is of 100 nM and 14.7 nM, respectively; high in vitro affinity for α₁-adrenoceptors, serotonin and muscarinic acetylcholine receptors.

Conditionnement

Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H301,H319,H361d,H410
• Conseils de prudence: P202 - P264 - P273 - P280 - P301 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 2
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable