A8199

N-Acetyl-L-cysteine

≥99% (TLC), suitable for cell culture, BioXtra

• Synonyme(s) : LNAC, NAC
• Formule linéaire : HSCH₂CH(NHCOCH₃)CO₂H
• Numéro CAS: 616-91-1
• Poids moléculaire : 163.19
• Numéro Beilstein : 1724426
• Numéro CE : 210-498-3
• Numéro MDL: MFCD00004880
• Code UNSPSC : 12352209
• ID de substance PubChem : 24891213
• Nomenclature NACRES : NA.26

Propriétés

• product name: N-Acetyl-L-cysteine, BioXtra, ≥99% (TLC)
• Gamme de produits: BioXtra
• Niveau de qualité: 300
• Pureté: ≥99% (TLC)
• Forme: powder
• Technique(s): cell culture | mammalian: suitable
• Impuretés: ≤0.002% Phosphorus (P); ≤0.1% Insoluble matter
• Résidus de calcination: ≤0.5%
• Couleur: white to off-white
• Pf: 106-108 °C (lit.)
• Solubilité: H₂O: 0.1 M at 20 °C, clear, colorless
• Traces de cations: Al: ≤0.0005%; Ca: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; NH₄⁺: ≤0.05%; Na: ≤0.1%; Pb: ≤0.001%; Zn: ≤0.0005%
• Application(s): cell analysis
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(=O)N[C@@H](CS)C(O)=O
• InChI: 1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
• Clé InChI: PWKSKIMOESPYIA-BYPYZUCNSA-N

Description

Application

N-Acetyl-L-cysteine has been used to study its protective effect against styrene-induced cochlear injuries in rats. It has also been used as a supplement in basal chemically-defined medium (BDM) for the culture of oligodendrocyte precursor cells.

Actions biochimiques/physiologiques

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H319
• Conseils de prudence: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Classification des risques: Eye Irrit. 2
• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)