939048

Lithium bis(trimethylsilyl)amide ChemBeads

• Synonyme(s) : Hexamethyldisilazane lithium salt ChemBeads
• Formule empirique (notation de Hill): LiC₆H₁₈NSi₂
• Poids moléculaire : 167.33
• Code UNSPSC : 12352100

Propriétés

• Description: Organic Salt
• Niveau de qualité: 100
• Forme: solid
• Composition: 14-16 wt% loading of base
• Pertinence de la réaction: core: lithium
• Chaîne SMILES: [Li]N([Si](C)(C)C)[Si](C)(C)C
• InChI: 1S/C6H18NSi2.Li/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
• Clé InChI: YNESATAKKCNGOF-UHFFFAOYSA-N

Description

Description générale

Lithium bis(trimethylsilyl)amide is a non-nucleophilic strong Brønsted base, which is generally soluble in most of the nonpolar organic solvents. It is most commonly employed in organic reactions.

Application

Base employed in generating enolates for the preparation of lactone precursors, pyranones, and cyclohexanes. Used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines.[6] Also used in a novel three-step synthesis of disubstituted 1,2,5-thiadiazoles. For general uses, product is also available in powdered form (324620)

Caractéristiques et avantages

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

Autres remarques

• High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads
• Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughout Experimentation
• ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

Informations sur la sécurité

• Pictogrammes: GHS02,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H228,H251,H314
• Conseils de prudence: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1B
• Risques supp: EUH014
• Code de la classe de stockage: 4.2 - Pyrophoric and self-heating hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 62.6 °F - closed cup
• Point d'éclair (°C): 17 °C - closed cup